National League champion Genève-Servette HC will go up against two ICEHL representatives, HC Bolzano (at home) and HC Innsbruck (on the road), Czech regular season winner Dynamo Pardubice (at home), French champion Rouen Dragons (at home), Slovakian champion HC Košice (on the road) and the Liiga's third seed Lukko Rauma.
Runner-up and second seed EHC Biel will face Finnish champion Tappara Tampere, Innsbruck as well as Košice at home and play the Växjö Lakers (SHL-champion), Swedish third seed Färjestad Karlstad and Czech second seed Vítkovice Ridera on the road.
Switzerland's third seed, the SC Rapperswil-Jona Lakers, have drawn home games against Tampere, Rauma, and Košice. Their travels will take them to Växjö, Vítkotice and to the Czech champion, Oceláři Třinec.